Nature Physics, Published online: 28 March 2025; doi:10.1038/s41567-025-02810-2
Light-switchable enzymes hold great promise for mediating molecular activations in living cells, yet their full potential in realizing versatile controls in nonlinear networks remains unexplored. Now, optical control is demonstrated over a key enzyme involved in animal cell division, and a diverse array of dynamic cell shapes is achieved by biochemically hacking an endogenous signalling circuit.
