Code
Φ-341
Level
Undergraduate
Category
C
Teacher
I. Kominis
ECTS
6
Hours
4
Semester
Winter
Display
Yes
Offered
No
Teacher Webpage
Goal of the course
The goal of this course is to introduce students to the modern and interdisciplinary field of biophysics. Students will learn how basic physics concepts they learn in other physics courses, like thermodynamics/statistical physics, electromagnetism and quantum mechanics, merge into the explanation of complexbiological systems.
Program
Monday 11:00-13:00 Amphitheater B
Thursday 13:00-15:00 Amphitheater B
Thursday 13:00-15:00 Amphitheater B
Syllabus
1) Biomolecules (3 classes)
Nucleic acids and DNA structure, hydrocarbons, lipids, amino acids and protein structure
2) Molecular bonding and interactions (5 classes)
Ionic bond, covalent bond, hydrogen bond, dispersion forces and van der Waals interactions
3) Biological thermodynamics (4 classes)
Free energy, entropy, chemical potential, chemical reaction rates, diffusion and transport
4) Experimental methods (6 classes)
Electroporation, electrophysiology, X-ray diffraction, nuclear magnetic resonance, infrared spectroscopy, fluorescence microscopy and spectroscopy
5) Modern topics I (4 classes)
Physical processes in the physiology of vision, action potential propagation in neurons
6) Modern topics II (4 classes)
Protein folding, molecular recognition, enzyme catalysis, molecular nanomachines
Nucleic acids and DNA structure, hydrocarbons, lipids, amino acids and protein structure
2) Molecular bonding and interactions (5 classes)
Ionic bond, covalent bond, hydrogen bond, dispersion forces and van der Waals interactions
3) Biological thermodynamics (4 classes)
Free energy, entropy, chemical potential, chemical reaction rates, diffusion and transport
4) Experimental methods (6 classes)
Electroporation, electrophysiology, X-ray diffraction, nuclear magnetic resonance, infrared spectroscopy, fluorescence microscopy and spectroscopy
5) Modern topics I (4 classes)
Physical processes in the physiology of vision, action potential propagation in neurons
6) Modern topics II (4 classes)
Protein folding, molecular recognition, enzyme catalysis, molecular nanomachines
Bibliography
1) Χαμόδρακας, Θέματα Μοριακής Βιοφυσικής, Συμμετρία
2) Παπαδόπουλος, Βιοφυσική-Αρχές Φυσικής Βιοχημείας, EMBRYO Publications
3) Kuriyan, Konforti & Wemmer, The Molecules of Life, Garland Science
4) Phillips, Kondev, Theriot, Garcia & Orme, Physical Biology of the Cell, Garland Science
5) Dill &Bromberg, Molecular Driving Forces, Garland Science
6) Scott, Neuroscience, a Mathematical Primer, Springer
7) Campbell, Biophysical Techniques, Oxford University Press
2) Παπαδόπουλος, Βιοφυσική-Αρχές Φυσικής Βιοχημείας, EMBRYO Publications
3) Kuriyan, Konforti & Wemmer, The Molecules of Life, Garland Science
4) Phillips, Kondev, Theriot, Garcia & Orme, Physical Biology of the Cell, Garland Science
5) Dill &Bromberg, Molecular Driving Forces, Garland Science
6) Scott, Neuroscience, a Mathematical Primer, Springer
7) Campbell, Biophysical Techniques, Oxford University Press
