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Principles of Medical Physics

Code
Φ-262
Level
Undergraduate
Category
C
Teacher
M. Tziraki
ECTS
6
Hours
4
Semester
Winter
Display
No
Offered
No
Goal of the course
The present is an introductory course on Medical Physics with the aim to familiarize the students with the applications of Physics in Medical Diagnostics. The majority of the course is dedicated to the study of the interactions of ionizing and non-ionizing radiation with matter. The former comprises a prerequisite on understanding the operational principles of the modern diagnostic techniques. Therefore it is recommended that the students have successfully attended the courses Φ-101, Φ-102 and Φ-103.
Program
Monday, 17:00-19:00, Room 3
Thursday, 18:00-20:00, Room 3
Syllabus
Ionizing Radiation
1. Structure of Matter. The Atom, Solids, Superconductivity, the Nucleus, Nuclear Fission and Fusion, Nuclear Spin and Nuclear Magnetic Moments.
2. Radioactive Decay. Nuclear stability and Decay, Alpha Decay, Beta Decay, Isomeric transitions, Decay Equations and Half-Life.
3. Interactions of Radiation. Characteristics of Interactions, Photoelectric Effect, Scattering effects Compton and Rαyleigh. Pair production, Interactions of Electrons, Interactions of Heavy Charged Particles, Interactions of Neutrons. X-ray and γ-ray radiations.
4. Production of X-rays. Conventional X-ray Tubes. Emission Spectra and Filtration.
5. Radiation Detectors. Ionization Chambers, Proportional counters, Geiger- Müller tubes, Solid and Liquid Scintillation detectors, Semiconductor detectors.
6. Radiation Quantity and Quality. Traditional versus Système International Units, Radiation Exposure, Units of Radiation Dose, Measurement of Radiation Dose .
7. Radiography. Fluoroscopy, Computed Tomography (CT). Priciples of Operation, Scan Motions, Dosimetry, Quality Control.
8. Instrumentation of Nuclear Imaging. Principles of Scintillation Camera operation, Gamma-ray Spectrometry. Positron Emission Tomography (PET).

Non Ionizing Radiation.
1. Ultrasound Waves. Wave Motion and Characteristics of Wave Propagation. Ultrasound Intensity and Velocity, Attenuation Coefficients Acoustic Impedance. Reflection, Refraction and Absorption. Piezoelectric Effect and Ultrasound Instrumentation. Doppler Effect.
2. Principles of NMR and Magnetic Resonance Imaging (MRI). Interaction of Nuclei with a static magnetic Field, Rotation and Precession. Quantum Mechanical Interpretation, Relaxation Processes T1 and T2. T1 and T2 for biologic matterials. MRI Instrumentation.
3. Optical Methods of medical Imaging. Interaction of Light with Tissue, Optical properties of Tissue. Human Vision. Ablation, Photochemistry, and Photoacoustic Effects. Optical coherence Tomography (OCT) and Optical Microscopy.
Bibliography
1. «Ιατρική Φυσική» – Κ.Ψαρράκος (Τόμοι Ι & ΙΙ)
2. «The Physics of Medical Imaging» - S Webb
3. «Τhe Physics of Radiology» – H.Ε. Johns and J.R Cunningham
4. «Introduction to radiobiological Physics and radiation Dosimetry»- F.H. Attix